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Year : 2014  |  Volume : 2  |  Issue : 1  |  Page : 3-7

Single nucleotide polymorphisms and periodontitis


1 Department of Oral Pathology and Microbiology; Department of Orthodontics, Faculty of Dentistry, Sebha University, Sebha Sebha University, Sebha, Libya
2 Department of Orthodontics, Faculty of Dentistry; Department of Periodontology and Implantology, Sebha University, Sebha Sebha University, Sebha, Libya
3 Department of Microbiology, Faculty of Medicine, Sebha University, Sebha, Libya
4 Department of Orthodontics, Faculty of Dentistry, Sebha University, Sebha, Libya
5 Department of Oral and maxillofacial surgery, Sebha University, Sebha, Libya
6 Department of Periodontics, Faculty of Dentistry, Benghazi University, Benghazi, Libya

Correspondence Address:
Ramalingam Karthikeyan
Department of Oral Pathology and Microbiology, Faculty of Dentistry, Sebha University, Sebha
Libya
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2348-1471.131556

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The susceptibility to various diseases is studied with association to genetic polymorphisms. Among these polymorphisms, single-nucleotide polymorphisms (SNPs) are very common throughout the genome. The recent advances in genetic assay techniques and increase in SNP databases are paving a way for investigation of susceptibility genes for periodontitis. This article attempts to review the role of SNP and its implications in periodontal disease and management.


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